3 Paroxetine For Premature Ejaculation

Paroxetine For Premature Ejaculation

PE is premature ejaculation; PE is known as one of the most common sexual disorders, affecting approximately 3 out of 10 men. PE is the inability to hold the ejaculation until both partners are satisfied.PE is classified into two types. Lifelong PE occurs at the beginning of your first sexual intercourse. Acquired PE develops after you had a previous sexual experience with ejaculatory problems.

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PE is premature ejaculation; PE is known as one of the most common sexual disorders, affecting approximately 3 out of 10 men. PE is the inability to hold the ejaculation until both partners are satisfied.PE is classified into two types. Lifelong PE occurs at the beginning of your first sexual intercourse. Acquired PE develops after you had a previous sexual experience with ejaculatory problems.

Over the past few decades, many therapies have been explored to treat PE like Selective serotonin reuptake inhibitors, topical anesthetics, a tricyclic antidepressant, surgery, etc.

 Although many were helpful but showed several side effects, Paroxetine was one of them. Still, Paraoxtine proved to be very effective and safer than other treatment options for PE. Waldinger, Marcel D. “Premature ejaculation.” Drugs 67.4 (2007)

Paroxetine acts as an antidepressant used to treat a variety of mood disorders. Paxil is the brand name of Paroxetine which belongs to the drug class Selective serotonin-reuptake inhibitors (SSRIs).

Paroxetine is an SSRI (Selective Serotonin reuptake inhibitor) that increases the amount of 5-hydroxytryptamine in postsynaptic membrane receptors and works by affecting ITEL (Intravaginal ejaculatory latency time) and thus delaying ejaculation. 

ITEL is the time taken by a man to ejaculate during vaginal penetration. ITEL is an element used to diagnose and treat a condition like PE.

Due to its sedative and practical use, it is recommended more for PE. It also helps to deal with sexual anxiety disorders. It is rarely recommended off-label for PE. Waldinger, Marcel D., Michiel W. Hengeveld, and Aeilko H. Zwinderman. “Paroxetine treatment of premature ejaculation: a double-blind, randomized, placebo-controlled study.” American Journal of Psychiatry 151.9 (1994)

Paroxetine seems to be more effective than other SSRIs like escitalopram, sertraline, and fluoxetine. The below study will give you all information regarding how effective Paroxetine is compared with other drugs. Barbui, Corrado, Toshiaki A. Furukawa, and Andrea Cipriani. “Effectiveness of paroxetine in treating acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials.” Cmaj 178.3 (2008):

The low level of serotonin leads to PE. Serotonin is a naturally arising chemical in the brain.

Paroxetine works by blocking the reuptake of chemical serotonin by neurons in the brain. It helps balance the level of serotonin or maintain brain chemical composition in a person.

So increasing serotonin levels in the brain can delay ejaculation. It also helps to enhance mood, boost energy levels and reduce anxiety. Zhang, Dong, et al. “Paroxetine in the treatment of premature ejaculation: a systematic review and meta-analysis.” BMC urology 19.1 (2019)

Yes, Paroxetine is a suitable treatment for PE as antidepressant drugs lead to delay ejaculation. Adults younger than 25 age should consult a health provider before consuming it.

Note-Regular use of Paroxetine for treating mental disorders in adolescents or young adults may increase the risk of suicidal thoughts and behavior.

Paroxetine is a generic drug available in the form of a tablet, capsule, extended-release tablet, or oral solution. Paroxetine tablets are taken in the morning or evening once per day with or without food. For PE, the paroxetine tablets need to be taken 1 or 2 hours before sex.

The controlled-release tablets or regular tablets need to be swallowed whole with water. Don’t crush or chew it. Your health provider will suggest a low dose starting, and after several days, the dose is increased. The manual dose of Paroxetine is between 10mg to 40mg.

Possible side effects of Paroxetine might be noticed within a week, which are listed below-

  • Paroxetine may affect your brain and body, and you might feel sleepy or drowsy and tired during the daytime.
  • The medication may lead you to sweat more or excessive sweating. Based on the surrounding temperature or your activity level or stress, you might accept. 
  • You may notice a change in your body structure or weight. It may suppress the sensation of hunger or decrease it, resulting in a change in appetite.
  • The medication may cause you to eat more and gain extra weight. It affects body metabolism, and your body will burn calories at a lower rate. 
  • Constipation is when stools are hard, dry, or lumpy that are difficult or painful to pass. 
  • The medication may affect bowel movements, resulting in loose and watery stools that are diarrhea.
  • The medication may lead to insomnia (sleep disorder) for a short period, often resolving over a few days up to a week.

Severe side effects can also occur, so you should immediately seek medical help.

The cost of Paroxetine is different in each country. The cost of Paroxetine differs from the brand name it is also available as an affordable generic drug.

The paroxetine cost varies in the strength of the dosage. The USA’s lowest price for a 10mg paroxetine tablet is $1.31 from the IndiaMART website.

Prescribed Paroxetine tablet seems to be consistently helpful. The process of buying Paroxetine online may be as follows-

  • Open the Google search engine and go to the search bar.
  • Type the name of the medication then a variety of websites will appear that are providing Paroxetine online.
  • Then rectify if the website is genuine or not.
  • You have to check each website properly and compare the medicine’s quality, quantity, and cost.
  • Don’t share your personal or financial information before placing the order.
  • If you find the medication on any website relevant to your requirement, place the order to purchase it. 

Premature ejaculation is a common factor and needs to be concerned about. Paroxetine treats depression, panic disorder, social anxiety disorder, etc. Paroxetine increases serotonin levels in the brain, which delays ejaculation. Paroxetine is effective on PE and comes in various forms. Paroxetine will take a few hours to prove its effectiveness.

Paroxetine may be helpful when prescribed but shows side effects. The medication is affordable and available on every online medication website.

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